Operationalising the quintuple helix in S3: Towards sustainable innovation in tourism

Authors

Keywords:

Quadruple Helix, Quintuple Helix, RIS3, Smart Specialization Strategy, Tourism

Abstract

This paper analyses how the Quintuple Helix (QUH) may be designed as a tool for a more efficient operation of the Smart Specialisation Strategy (S3) and its current evolution towards the Smart Specialisation Strategies for sustainable and inclusive growth (S4+), considering tourism as a priority domain and how both can enhance each other. By combining the natural environment and societal actors into policy design, the study argues that adding the QUH model into S3 improves innovation governance. The proposed QUH–S4+ framework links five helices: academia, industry, government, civil society, and the natural environment, forming a collaborative system for sustainable and innovation-driven regional development. This approach assigns a pivotal role to the natural environment as a catalyst for knowledge production and innovation. The QUH emphasises cohesive interaction and knowledge sharing across cultural, political, and economic systems, where cross-regional cooperation can particularly benefit less developed regions that embrace green technologies aligned with the European Green Deal. Innovative technology solutions can completely transform tourism, making the vision of smart tourism a reality. The natural environment is a crucial element of the knowledge-building process, and innovation is particularly crucial since it helps to thrive, better serve humankind, and commit to green technology more successfully. Methodologically, the paper conducts a conceptual, theory-building review, deriving operational propositions and a policy checklist that translates the QUH framework into S3/S4+ implementation in tourism.

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References

Aarstad, J., Kvitastein, O. A., & Jakobsen, S. E. (2016). Related and unrelated variety in a tourism context. Annals of Tourism Research, 57, 254–256. https://doi.org/10.1016/j.annals.2015.12.002

Asheim, B., Grillitsch, M., & Trippl, M. (2017). Smart specialization as an innovation-driven strategy for economic diversification: Examples from Scandinavian regions. In Advances in the Theory and Practice of Smart Specialization (pp. 73–97). Elsevier Inc. https://doi.org/10.1016/b978-0-12-804137-6.00004-8

Bailey, D., & De Propris, L. (2019). Industry 4.0, regional disparities and transformative industrial policy. Regional Studies Policy Impact Books, 1(2), 67–78. https://doi.org/10.1080/2578711x.2019.1621102

Barcellos-Paula, L., De la Vega, I., & Gil-Lafuente, A. M. (2021). The quintuple helix of innovation model and the sdgs: Latin-American countries’ case and its forgotten effects. Mathematics, 9(4), 1–24. https://doi.org/10.3390/math9040416

Barzotto, M., Corradini, C., Fai, F. M., Labory, S., & Tomlinson, P. R. (2019). Revitalizing lagging regions. Routledge. https://doi.org/10.4324/9780367422745

Bečić, E., & Švarc, J. (2015). Smart specialization in Croatia: Between the cluster and technological specialization. Journal of the Knowledge Economy, 6(2), 270–295. https://doi.org/10.1007/s13132-015-0238-7

Benner, M. (2017). From clusters to smart specialization: Tourism in institution-sensitive regional development policies. Economies, 5(3), 26. https://doi.org/10.3390/economies5030026

Benner, M. (2020). Tourism in the context of smart specialization: The example of Montenegro. Current Issues in Tourism, 23(21), 2624–2630. https://doi.org/10.1080/13683500.2019.1687663

Camagni, R., & Capello, R. (2013). Regional innovation patterns and the EU regional policy reform: Towards smart innovation policies. Growth and Change, 44(2), 355–389. https://doi.org/10.1007/978-3-319-57807-1_16

Carayannis, E. G., & Campbell, D. F. J. (2009). “Mode 3” and “Quadruple Helix”: Toward a 21st century fractal innovation ecosystem. International Journal of Technology Management, 46(3–4), 201–234. https://doi.org/10.1504/ijtm.2009.023374

Carayannis, E. G., & Campbell, D. F. J. (2010). Triple helix, quadruple helix and quintuple helix and how do knowledge, innovation and the environment relate to each other? A proposed framework for a trans-disciplinary analysis of sustainable development and social ecology. International Journal of Social Ecology and Sustainable Development, 1(1), 41–69. https://doi.org/10.4018/jsesd.2010010105

Carayannis, E. G., & Campbell, D. F. J. (2011). Open innovation diplomacy and a 21st century fractal research, education and innovation (FREIE) ecosystem: Building on the quadruple and quintuple helix innovation concepts and the “Mode 3” knowledge production system. Journal of the Knowledge Economy, 2(3), 327–372. https://doi.org/10.1007/s13132-011-0058-3

Carayannis, E. G., & Rakhmatullin, R. (2014). The quadruple/quintuple innovation helixes and smart specialisation strategies for sustainable and inclusive growth in Europe and beyond. Journal of the Knowledge Economy, 5(2), 212–239. https://doi.org/10.1007/s13132-014-0185-8

Carayannis, E. G., Barth, T. D., & Campbell, D. F. (2012). The Quintuple Helix innovation model: Global warming as a challenge and driver for innovation. Journal of Innovation and Entrepreneurship, 1(1), 2. https://doi.org/10.1186/2192-5372-1-2

de Almeida Leite, E. M., Audretsch, D., & Leite, A. (2025). Integrating philosophy and psychology to enhance creativity and innovation in entrepreneurship: The W.O.M.B. model. Journal of Technology Transfer, 50, 1396–1415. https://doi.org/10.1007/s10961-024-10142-1

Del Vecchio, P., & Passiante, G. (2017). Is tourism a driver for smart specialization? Evidence from Apulia, an Italian region with a tourism vocation. Journal of Destination Marketing and Management, 6(3), 163–165. https://doi.org/10.1016/j.jdmm.2016.09.005

EC. (2013). European Tourism Indicator System Toolkit For Sustainable Destinations. http://ec.europa.eu/enterprise/sectors/tourism/sustainable-tourism/indicators/index_en.htm

EC. (2014). National/Regional Innovation Strategies for Smart Specialisation (RIS3) (Issue March 2014).

EC. (2016). Guide on EU funding for the tourism sector (2014-2020). https://doi.org/10.2873/251606

EC. (2025). Regional Innovation Scoreboard 2025. https://doi.org/10.2777/2313906

Erkuş-Öztürk, H. (2016). (Un)related variety, urban milieu and tourism-company differentiation. Tourism Geographies, 18(4), 422–444. https://doi.org/10.1080/14616688.2016.1200129

Etzkowitz, H., & Leydesdorff, L. (1997). Universities and the global knowledge economy: A triple helix of university–industry–government relations. Pinter.

Etzkowitz, H., & Leydesdorff, L. (2000). The dynamics of innovation: From national systems and “Mode 2” to a triple helix of university–industry–government relations. Research Policy, 29(2), 109–123. https://doi.org/10.1016/S0048-7333(99)00055-4

European Commission. (2014). National/regional innovation strategies for smart specialisation (RIS3). https://doi.org/10.2776/65746

European Commission. (2016). Guide on EU funding for the tourism sector (2014–2020). https://doi.org/10.2873/251606

European Network of Living Labs (ENoLL). (2024). Urban Leisure and Tourism Living Lab: Redefining tourism through place-based innovation. Retrieved from https://enoll.org/story/urban-leisure-and-tourism-living-lab-redefining-tourism-through-place-based-innovation/

European Network of Living Labs (ENoLL). (2025). Alimara Living Lab (ALL). Retrieved from https://enoll.org/member/alimara-living-lab/

Foray, D. (2014a). From smart specialization to smart specialization policy. European Journal of Innovation Management, 17(4), 492–507. https://doi.org/10.1108/EJIM-09-2014-0096

Foray, D. (2014b). Smart specialization: Opportunities and challenges for regional innovation policy. Routledge.

Foray, D., David, P. A., & Hall, B. (2009). Smart specialization – The concept. Knowledge Economists Policy Brief, 9(85). http://ec.europa.eu/invest-in-research/pdf/download_en/kfg_policy_brief_no9.pdf

Foray, D., Goddard, J., Beldarrain, X. G., Landabaso, M., McCann, P., Morgan, K., Nauwelaers, C., & Ortega-Argilés, R. (2012). Guide to research and innovation strategies for smart specialization (RIS3). https://doi.org/10.2776/65746

Gibbons, M., Limoges, C., Nowotny, H., Schwartzman, S., Scott, P., & Trow, M. (1994). The new production of knowledge: The dynamics of science and research in contemporary societies. Sage.

Junta de Comunidades de Castilla-La Mancha. (2023, September 18). El Gobierno regional desarrolla una plataforma tecnológica con inteligencia artificial para impulsar la innovación en el turismo de Castilla-La Mancha

Lazzeretti, L., Capone, F., & Innocenti, N. (2016). The impact of related variety on tourist destinations: An analysis of tourist firms clustering. In F. Capone (Ed.), Tourist clusters, destinations and competitiveness (pp. 62–80). Routledge. https://doi.org/10.4324/9781315709536

Leite, E., & Leite, A. (2024). Strategic imperatives for bridging the innovation divide: The OSEAN initiative in European outermost regions. In INTED2024 Proceedings (pp. 3426–3434).

Leite, E., Mota, L., Lousada, S., & Leite, A. (2022). Standardized reading of sustainable tourism indicators for ultraperipheral regions. Sustainability, 14(21), 14076. https://doi.org/10.3390/su142114076

Leydesdorff, L. (2012). The triple helix, quadruple helix, …, and an N-tuple of helices: Explanatory models for analyzing the knowledge-based economy? Journal of the Knowledge Economy, 3(1), 25–35. https://doi.org/10.1007/s13132-011-0049-4

Lundvall, B.-Å. (1992). National systems of innovation: Towards a theory of innovation and interactive learning. Pinter.

McCann, P., & Ortega-Argilés, R. (2015). Smart specialization, regional growth and applications to European Union cohesion policy. Regional Studies, 49(8), 1291–1302. https://doi.org/10.1080/00343404.2013.799769

McCann, P., & Soete, L. (2020). Place-based innovation for sustainability. https://doi.org/10.2760/250023

Mota, L., Leite, E., & Ghasemi, V. (2024). Exploring the impact of climate change on lodging establishments: A systematic literature review. Quality & Quantity. https://doi.org/10.1007/s11135-024-01834-9

Provenzano, V., Arnone, M., & Seminara, M. R. (2018). The links between smart specialization strategy, the quintuple helix model and living labs. In Green Energy and Technology (Vol. 0). Springer International Publishing. https://doi.org/10.1007/978-3-319-75774-2_38

Retrieved from https://www.castillalamancha.es/actualidad/notasdeprensa/el-gobierno-regional-desarrolla-una-plataforma-tecnol%C3%B3gica-con-inteligencia-artificial-para-impulsar

Romão, J. (2020a). Tourism, smart specialization, growth, and resilience. Annals of Tourism Research, 84, 102995. https://doi.org/10.1016/j.annals.2020.102995

Romão, J. (2020b). Variety, smart specialization and tourism competitiveness. Sustainability, 12(14), 5765. https://doi.org/10.3390/su12145765

Romão, J., & Nijkamp, P. (2018). Spatial impacts assessment of tourism and territorial capital: A modelling study on regional development in Europe. International Journal of Tourism Research, 20(6), 819–829. https://doi.org/10.1002/jtr.2234

Sardinha, L., Vieira, M., de Sousa, Á. S., & Leite, E. (2023). Digital nomads — The case of the Autonomous Region of Madeira. Journal of Entrepreneurial Researchers, 1(2), 55–69. https://doi.org/10.29073/jer.v1i2.14

Schot, J., & Steinmueller, W. E. (2018). Three frames for innovation policy: R&D, systems of innovation and transformative change. Research Policy, 47(9), 1554–1567. https://doi.org/10.1016/j.respol.2018.08.011

Schwabe, O., Leite, E., Lopez, J. D., Addi, K., & Almeida, N. (2025). Critical assets and value networks in resilient innovation ecosystems in the EU outermost regions. CIB Conferences, 1, Article 26. https://doi.org/10.7771/3067-4883.2141

Sudiana, K., Sule, E. T., Soemaryani, I., & Yunizar, Y. (2020). The development and validation of the penta helix construct. Business: Theory and Practice, 21(1), 136–145. https://doi.org/10.3846/btp.2020.11231

Torres-Delgado, A., & Palomeque, F. L. (2014). Measuring sustainable tourism at the municipal level. Annals of Tourism Research, 49, 122–137. https://doi.org/10.1016/j.annals.2014.09.003

Turismo de Portugal. (2024, May 28). European Green Deal / Pacto Ecológico Europeu. https://business.turismodeportugal.pt/en/Conhecer/Oportunidades_UE/programas-iniciativas/Pages/european-green-deal-pacto-ecologico-europeu.aspx

Vezzani, V., Canina, M., Bruno, C., & Leite, E. (2024). Editorial—Digital creativity for developing digital maturity future skills. Journal of Entrepreneurial Researchers, 2(1), 1–4. https://doi.org/10.29073/jer.v2i1.32

Weidenfeld, A. (2018). Tourism diversification and its implications for smart specialization. Sustainability, 10(2), 319. https://doi.org/10.3390/su10020319

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Published

2025-11-18

How to Cite

Vieira, Élia, & Leite, A. (2025). Operationalising the quintuple helix in S3: Towards sustainable innovation in tourism. Journal of Entrepreneurial Researchers, 4(1). Retrieved from https://jerhub.org/index.php/jer/article/view/55